Yang Li, Qing Zhao, Shuangge Ma

【Abstract】

Biostatistics is the application of statistics to the field of biological science, medical science, public health, and agriculture. The beginning of the era of precision medicine has witnessed the rapid advancement in the field of biostatistics. Yet the growing dimension, complexity, and heterogeneity in “big data” have brought about a lot of new challenges to biostatistics researchers in theory and application alike. The article focuses on the recent development in four different areas including epidemiology, clinical trials, survival analysis, and genomic data analysis, discusses the challenges with further development based on introducing the basic concepts.

【Keywords】

epidemiology, clinical trial, survival analysis, gene data analysis