Time：2021/12/21 14:30-15:30

Form：Tencent Meeting（ID：743 688 012）

Topic：Chicken, egg, or both: Epidemiological study of sleep and neurodegeneration

Abstract:

Growing evidence suggests a close link between sleep disturbances and adverse health outcomes in older adults. However, many research gaps remain to be filled. In this presentation, Dr. Leng will present a series of epidemiological studies, both cross-sectional and longitudinal, that focused on sleep, daytime napping and disruption of circadian rhythms as measured objectively by actigraphy and incident Alzheimer’s disease (AD) and Parkinson’s disease (PD). Furthermore, she will highlight their recent findings using data from the UK biobank and Mendellian randomization to explore the nature and direction of the relationship. Finally, Leng will discuss the implications of their findings, i.e. whether sleep disturbances are prodromal, symptom or risk factor of neurodegenerative diseases.

Resume:

Dr. Yue Leng is an Assistant Professor at the University of California, San Francisco (UCSF) and senior Atlantic Fellow at the Global Brain Health Institute. Her research is focused on the relationship between sleep and neurodegeneration. She has an MPhil and PhD in Epidemiology from the University of Cambridge and Bachelor in Preventive Medicine from Sun-Yat Sen University. She has published in leading journals, including Lancet Neurology, JAMA Neurology, etc as First and Corresponding author. Her research is funded by an NIH K99/R00 award, and has received awards from the Alzheimer`s Association, etc. Her work has been featured in mass media including the CNN, the Reuters, the Times, etc.